Understanding how hepatitis B virus spreads in the liver
NIH: Spatial Models of Intrahepatic Hepatitis Virus Propagation in Humans
['FUNDING_R01'] · TRIAD NATIONAL SECURITY, LLC · NIH-11012379
This study is looking at how the hepatitis B virus affects the liver and aims to find better ways to treat it, especially for people who also have HIV or hepatitis C, so that patients can have more effective treatment options and possibly even a cure.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | TRIAD NATIONAL SECURITY, LLC (nih funded) |
| Locations | 1 site (Los Alamos, UNITED STATES) |
| Trial ID | NIH-11012379 on ClinicalTrials.gov |
What this research studies
This research investigates the complex lifecycle of the hepatitis B virus (HBV) and its impact on liver disease. By analyzing unique liver tissue samples and utilizing advanced techniques for single-cell analysis, the study aims to develop new models that can better inform clinical treatments for chronic hepatitis B infection. The goal is to improve therapeutic strategies that can effectively target and eliminate the virus, especially in patients with co-infections like HIV or hepatitis C. Patients may benefit from insights gained into more effective treatment options and potential cures for chronic hepatitis B.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with chronic hepatitis B, particularly those with co-infections such as HIV or hepatitis C.
Not a fit: Patients who do not have chronic hepatitis B or related liver diseases may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments and potential cures for chronic hepatitis B infection.
How similar studies have performed: Previous research has shown promise in developing innovative treatments for hepatitis B, but this approach aims to provide novel insights that have not yet been fully explored.
Where this research is happening
Los Alamos, UNITED STATES
- TRIAD NATIONAL SECURITY, LLC — Los Alamos, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: RIBEIRO, RUY M — TRIAD NATIONAL SECURITY, LLC
- Study coordinator: RIBEIRO, RUY M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome Virus