Portable brain scanner that links brain signals to brain structure

Non-cryogenic Fieldable Interleaved Magnetoencephalography and Magnetic Resonance Imaging based on Multichannel Atomic Magnetometers

NIH-funded research Triad National Security, LLC · NIH-11248011

A new portable device will combine non-cryogenic magnetic sensors and ultra-low-field MRI to map fast brain signals together with anatomy for people with brain disorders like epilepsy.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionTriad National Security, LLC NIH-funded
Lab location1 site (Los Alamos, UNITED STATES)
Project IDNIH-11248011 on NIH RePORTER

What this research studies

This project will build a compact system that alternates between magnetoencephalography (MEG) and ultra-low-field MRI using atomic magnetometers to record brain activity and anatomy in the same coordinate system. It replaces bulky, cryogenically cooled sensors and heavy shielding with room-temperature alkali-metal vapor sensors to make the technology more practical for clinics. By directly linking precise timing of brain signals to specific brain structures, the device aims to help doctors locate problem areas such as seizure foci and plan surgeries more accurately. Early work focuses on creating a 16-channel sensor module and testing combined imaging performance on human brains.

Who could benefit from this research

Good fit: People with focal brain disorders—especially those with epilepsy who need better localization of seizure sources or pre-surgical mapping—are the most likely candidates.

Not a fit: Patients who require high-field MRI detail, have MRI-incompatible implants, or whose conditions do not involve focal brain electrical activity may not benefit from this approach.

Why it matters

Potential benefit: If successful, this could make precise brain mapping more accessible and improve diagnosis and surgical planning for conditions such as epilepsy.

How similar studies have performed: Combining MEG and MRI has been done using cryogenic SQUID sensors in shielded rooms, but using portable atomic magnetometers for interleaved, non-cryogenic imaging is novel and less clinically tested.

Where this research is happening

Los Alamos, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Brain DiseasesBrain Disorders
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.