Understanding how gut bacteria influence lung immune responses in rheumatoid arthritis
Microbiota Control Lung Th17 Cell Response and Plasticity Leading to Autoimmune Lung Disease
This study is looking at how the bacteria in your gut might influence your lung health if you have rheumatoid arthritis, with the hope of finding new ways to help prevent lung problems related to the condition.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ohio State University NIH-funded |
| Lab location | 1 site (Columbus, UNITED STATES) |
| Project ID | NIH-10687275 on NIH RePORTER |
What this research studies
This research investigates the connection between gut bacteria and lung immune responses in patients with rheumatoid arthritis (RA). It focuses on how certain gut microbes can affect the behavior of immune cells in the lungs, potentially leading to lung complications associated with RA. The study aims to explore the mechanisms by which these gut bacteria promote specific immune responses and how these responses may contribute to lung disease. By examining the interactions between gut microbiota and lung immune cells, the research seeks to uncover new insights into the treatment of lung issues in RA patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with rheumatoid arthritis who are experiencing lung complications.
Not a fit: Patients without rheumatoid arthritis or those not experiencing lung issues related to their condition may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies that improve lung health in patients with rheumatoid arthritis.
How similar studies have performed: Previous research has shown promising results in understanding the gut-lung axis, indicating that this approach may lead to significant advancements in treatment.
Where this research is happening
Columbus, UNITED STATES
- Ohio State University — Columbus, United States (Active)
Researchers
- Principal investigator: Wu, Hsin-Jung Joyce — Ohio State University
- Study coordinator: Wu, Hsin-Jung Joyce
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.