Understanding how gut bacteria affect health and disease
Statistical modeling of cross-sample variation and learning of latent structures in microbiome sequencing data
['FUNDING_R01'] · DUKE UNIVERSITY · NIH-10893383
This study is looking at the tiny bacteria in our bodies and how they might be connected to health issues like diabetes and obesity, with the goal of helping patients understand how these bacteria affect their health and treatment.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | DUKE UNIVERSITY (nih funded) |
| Locations | 1 site (DURHAM, UNITED STATES) |
| Trial ID | NIH-10893383 on ClinicalTrials.gov |
What this research studies
This research focuses on the bacterial communities in the human body, known as microbiota, and their links to various diseases like diabetes and obesity. By analyzing microbiome sequencing data, the project aims to develop new statistical models and algorithms that can better understand the complex relationships among different bacterial species and their impact on health. Patients may benefit from improved insights into how their microbiome influences their health and treatment responses. The research employs advanced statistical techniques to address the unique challenges posed by microbiome data.
Who could benefit from this research
Good fit: Ideal candidates include individuals with conditions linked to microbiota, such as Type 2 diabetes, obesity, or inflammatory bowel disorders.
Not a fit: Patients without any microbiome-related health issues or those not affected by the diseases being studied may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better personalized treatments based on an individual's microbiome composition.
How similar studies have performed: Other research has shown promising results in understanding the microbiome's role in health, indicating that this approach could yield valuable insights.
Where this research is happening
DURHAM, UNITED STATES
- DUKE UNIVERSITY — DURHAM, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MA, LI — DUKE UNIVERSITY
- Study coordinator: MA, LI
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acute Disease, Adult-Onset Diabetes Mellitus, Cancer Patient, Cancers, Chronic Disease