Understanding how glycophagy affects metabolism
Official title: Defining the mechanisms of the glycophagy shunt and its role in metabolism
Funded at Lsu Pennington Biomedical Research Ctr · NIH-10934905 · Data updated 2026-11-12
This study is looking at how a process called glycophagy helps our cells break down glycogen for energy, which is important for managing blood sugar levels, and it could lead to better treatments for people with metabolic diseases.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Lsu Pennington Biomedical Research Ctr NIH-funded |
| Lab location | 1 site (Baton Rouge, United States) |
| Project start | August 1, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2024 |
| Award (this year) | $355,111 |
| NIH project number | 1R35GM154665-01 |
| Project ID | NIH-10934905 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with metabolic diseases, particularly those related to glucose metabolism like diabetes or glycogen storage diseases.
✕Less likely to help
Patients with conditions unrelated to glucose metabolism or those not affected by metabolic diseases may not benefit from this research.
What this research studies
This research investigates the role of glycophagy, a process of glycogen degradation, in cellular metabolism. By using genetically modified cells and mice, the researchers aim to uncover how glycophagy contributes to the glycogen shunt, which is crucial for glucose metabolism. The study will develop innovative tools to better understand these mechanisms, potentially leading to insights into various metabolic diseases. Patients may benefit from improved understanding of how their conditions relate to glucose metabolism.
Why it matters
Potential benefit: If successful, this research could lead to new insights and treatments for metabolic diseases such as diabetes, cancer, and heart disease.
How similar studies have gone: While the specific focus on glycophagy is relatively novel, previous research has shown success in understanding glucose metabolism and its implications for various diseases.
Where this research is happening
-
Lsu Pennington Biomedical Research Ctr
Baton Rouge, United States Active
Researchers
- Principal investigator: Heden, Timothy D. — Lsu Pennington Biomedical Research Ctr
- Study coordinator: Heden, Timothy D.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.