Understanding how genetics and environment contribute to type 2 diabetes
Cataloging multi-ancestry 'omic readouts of the environmental and genetic determinants of type 2 diabetes
['FUNDING_R01'] · HARVARD MEDICAL SCHOOL · NIH-10978543
This study is looking at how your genes and your environment work together to affect your risk of developing type 2 diabetes, so you can learn more about your own risk and get personalized tips for prevention.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | HARVARD MEDICAL SCHOOL (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-10978543 on ClinicalTrials.gov |
What this research studies
This research investigates the complex interactions between genetic factors and environmental influences that lead to the development of type 2 diabetes (T2D). By analyzing diverse populations, the study aims to identify how these factors contribute to insulin resistance and beta-cell dysfunction. It utilizes advanced blood assays to explore the relationships between genetic predispositions and environmental exposures, ultimately seeking to create predictive models for T2D risk. Patients may benefit from insights into their own risk factors and tailored prevention strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals from diverse backgrounds who are at risk for or have been diagnosed with type 2 diabetes.
Not a fit: Patients who do not have any risk factors for type 2 diabetes or those with other unrelated health conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to personalized prevention strategies for type 2 diabetes based on individual genetic and environmental profiles.
How similar studies have performed: Previous research has shown promise in understanding the genetic and environmental factors of diabetes, but this approach is innovative in its comprehensive analysis across diverse populations.
Where this research is happening
BOSTON, UNITED STATES
- HARVARD MEDICAL SCHOOL — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: PATEL, CHIRAG J. — HARVARD MEDICAL SCHOOL
- Study coordinator: PATEL, CHIRAG J.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Adult-Onset Diabetes Mellitus, Atherosclerotic Cardiovascular Disease