Understanding how genetics and environment affect obesity and energy balance

Epigenetics of energy homeostasis, bioenergetics and obesity

NIH-funded research University of Texas San Antonio · NIH-10263385

This study is looking at how our genes and the environment around us can affect weight gain, especially in Hispanic children and adults, by checking things like diet, exercise, and body composition to find out what makes some people more at risk for obesity.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Texas San Antonio NIH-funded
Lab location1 site (San Antonio, United States)
Project IDNIH-10263385 on NIH RePORTER

What this research studies

This research investigates the complex relationship between genetics, environmental factors, and obesity by focusing on energy homeostasis, which is the balance of energy intake and expenditure. Using advanced DNA sequencing technologies, the study aims to identify specific epigenetic markers that influence obesity risk. Participants will be involved in assessments that include body composition, dietary habits, and physical activity levels, providing a comprehensive view of factors contributing to obesity. The research particularly emphasizes the experiences of Hispanic children and adults, aiming to uncover unique genetic and environmental interactions.

Who could benefit from this research

Good fit: Ideal candidates for this research include adults, especially those with a family history of obesity or related metabolic conditions.

Not a fit: Patients who are not affected by obesity or do not have any related health concerns may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new strategies for preventing and treating obesity, particularly in populations at higher risk.

How similar studies have performed: Previous research has shown promising results in understanding the genetic and environmental factors contributing to obesity, indicating that this approach has potential for success.

Where this research is happening

San Antonio, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Atherosclerotic Cardiovascular Diseaseatherosclerotic diseaseatherosclerotic vascular disease
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.