Understanding how genetics affect smoking-related blood vessel problems
Delineating the Genetic Susceptibility of Smoking-Induced Vascular Dysfunction
This study is looking at how our genes might affect how smoking impacts heart health, and it’s designed to help people understand their own risks related to smoking and heart problems.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Utah NIH-funded |
| Lab location | 1 site (Salt Lake City, United States) |
| Project ID | NIH-10895572 on NIH RePORTER |
What this research studies
This research investigates how genetic differences among individuals influence their susceptibility to cardiovascular issues caused by smoking. The project utilizes advanced techniques in bioinformatics and drug discovery, alongside insights from environmental health and immunology. Patients may benefit from a better understanding of their own genetic risks related to smoking and cardiovascular health. The research is led by Dr. Hongchao Guo, who is being mentored by experts in cardiovascular disease and immune dysfunction.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with a history of smoking or those at risk for cardiovascular diseases due to smoking.
Not a fit: Patients who have never smoked and do not have a genetic predisposition to cardiovascular diseases may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to personalized strategies for preventing smoking-related cardiovascular diseases based on genetic profiles.
How similar studies have performed: Previous research has shown promise in understanding genetic factors in cardiovascular diseases, indicating that this approach could yield valuable insights.
Where this research is happening
Salt Lake City, United States
- University of Utah — Salt Lake City, United States (Active)
Researchers
- Principal investigator: Guo, Hongchao — University of Utah
- Study coordinator: Guo, Hongchao
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.