Understanding how genetics affect immune responses to COVID-19
Immunogenetics of COVID-19 Immune Response
This study is looking at how our genes might affect how we respond to COVID-19 and its vaccines, so we can better understand who might need different kinds of protection and help create more personalized vaccination plans.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project ID | NIH-10988035 on NIH RePORTER |
What this research studies
This research investigates the genetic factors that influence how individuals respond to COVID-19 infections and vaccinations. By examining variations in genes and their associations with immune responses, the study aims to identify specific genetic markers that could predict how well a person will respond to the virus or a vaccine. The approach includes comprehensive genome-wide association studies (GWAS) and phenome-wide association studies (PheWAS) to uncover the complex interactions between genetics and immune response. This research could lead to personalized vaccination strategies and improved understanding of immunity against COVID-19.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals who have been vaccinated against COVID-19 or have had a COVID-19 infection.
Not a fit: Patients who have not been vaccinated or infected with COVID-19 may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective vaccines and treatments tailored to individual genetic profiles.
How similar studies have performed: Previous research has successfully identified genetic factors influencing immune responses to other viral vaccines, suggesting a promising avenue for similar findings in COVID-19.
Where this research is happening
Rochester, United States
- Mayo Clinic Rochester — Rochester, United States (Active)
Researchers
- Principal investigator: Kennedy, Richard B — Mayo Clinic Rochester
- Study coordinator: Kennedy, Richard B
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.