Understanding how genetic variations affect neuropsychiatric disorders
1/9: Dissecting the effects of genomic variants on nenriched for neuropsychiatric disorderseurobehavioral dimensions in CNVs
This study is looking at how certain genetic changes might affect conditions like anxiety, ADHD, and autism, helping us understand how these genes can influence mental health and behavior in people who already have known genetic conditions.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-10597092 on NIH RePORTER |
What this research studies
This research investigates the impact of specific genetic variations, known as copy number variants (CNVs), on a range of neuropsychiatric disorders such as anxiety, ADHD, and autism. By focusing on patients with known genetic conditions, the study aims to clarify how these genetic factors contribute to mental health issues and their symptoms. The research combines genetic analysis with behavioral assessments to create models that predict risk for developing these disorders. This approach seeks to enhance our understanding of the complex interplay between genetics and environmental influences on mental health.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with neuropsychiatric disorders who have known genetic variations associated with these conditions.
Not a fit: Patients without neuropsychiatric disorders or those whose conditions are not linked to the specific genetic variations being studied may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved risk prediction and personalized treatment strategies for individuals with neuropsychiatric disorders.
How similar studies have performed: Previous research has shown promising results in understanding the genetic basis of neuropsychiatric disorders, indicating that this approach could yield valuable insights.
Where this research is happening
Philadelphia, United States
- University of Pennsylvania — Philadelphia, United States (Active)
Researchers
- Principal investigator: Gur, Raquel E — University of Pennsylvania
- Study coordinator: Gur, Raquel E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.