Understanding how genetic variations affect health
Mechanisms of Action of Natural Genetic Variation
This study is looking at how different genes can affect your health and risk of disease, using yeast to help figure out which gene variations matter and how they work together, with the goal of making medical care more personalized for everyone.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-11063153 on NIH RePORTER |
What this research studies
This research investigates how different genetic variations can influence disease risk and health outcomes. By using a model organism, budding yeast, the team aims to identify which genetic variants are responsible for complex traits and how they interact with each other and the environment. The project will analyze various molecular factors, such as gene expression and protein levels, to better predict how these genetic variations impact individual patients. This knowledge could lead to more personalized approaches in medicine, helping to clarify the significance of genetic variants in health.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with known genetic variations who are at risk for complex diseases.
Not a fit: Patients without any genetic variations or those with conditions not influenced by genetic factors may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could enhance the ability to predict disease risk based on genetic information, leading to more tailored and effective treatments for patients.
How similar studies have performed: Previous research has shown promise in understanding genetic variations and their effects on health, making this approach both relevant and potentially impactful.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: Jarosz, Daniel — Stanford University
- Study coordinator: Jarosz, Daniel
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.