Understanding how genetic variations affect behavior in neuropsychiatric disorders
3/9 Dissecting the effects of genomic variants on neurobehavioral dimensions in CNVs enriched for neuropsychiatric disorders
This study is looking at how certain genetic differences might affect conditions like anxiety and attention disorders, helping us understand how genes and the environment work together to influence mental health, which could lead to better ways to diagnose and treat these issues.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project ID | NIH-10834136 on NIH RePORTER |
What this research studies
This research investigates the impact of specific genetic variations, known as copy number variants (CNVs), on various neurobehavioral conditions such as anxiety and attention disorders. By focusing on patients with known genetic profiles, the study aims to clarify how these genetic factors interact with environmental influences to shape mental health outcomes. The research employs advanced computational methods to analyze the relationship between genetic data and behavioral symptoms, potentially leading to better diagnostic and treatment strategies for affected individuals.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with neuropsychiatric disorders who have known genetic variations, particularly those involving the 22q11.2 and 16p11.2 loci.
Not a fit: Patients without identifiable genetic variations or those with idiopathic neuropsychiatric disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for patients with neuropsychiatric disorders linked to genetic factors.
How similar studies have performed: Previous research has shown promise in understanding the genetic underpinnings of neuropsychiatric disorders, indicating that this approach could yield valuable insights.
Where this research is happening
Los Angeles, United States
- University of California Los Angeles — Los Angeles, United States (Active)
Researchers
- Principal investigator: Bearden, Carrie E — University of California Los Angeles
- Study coordinator: Bearden, Carrie E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.