Understanding how genetic variations affect behavior in neuropsychiatric disorders.
6/9: Dissecting the effects of genomic variants on neurobehavioral dimensions in CNVs enriched for neuropsychiatric disorders.
This study is looking at how certain genetic changes might affect behaviors related to mental health issues like anxiety and attention disorders, and it's designed for people with known genetic conditions to help us better understand the link between genes and mental health.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Sainte-Justine University Hospital Ctr NIH-funded |
| Lab location | 1 site (Montreal, Canada) |
| Project ID | NIH-10811617 on NIH RePORTER |
What this research studies
This research investigates the impact of specific genetic variations, known as copy number variants (CNVs), on neurobehavioral traits associated with various psychiatric disorders. By focusing on patients with known genetic conditions, the study aims to clarify how these genetic factors contribute to a range of mental health issues, including anxiety and attention disorders. The research employs a combination of genetic analysis and behavioral assessments to build predictive models of risk for these conditions. This approach seeks to enhance our understanding of the complex interplay between genetics and environmental influences on mental health.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with neuropsychiatric disorders linked to specific genetic variants, particularly those with 22q11.2 and 16p11.2 CNVs.
Not a fit: Patients without neuropsychiatric disorders or those not carrying the specific genetic variants being studied may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnosis and treatment strategies for individuals with neuropsychiatric disorders.
How similar studies have performed: Previous research has shown promising results in understanding the genetic basis of neuropsychiatric disorders, suggesting that this approach could yield valuable insights.
Where this research is happening
Montreal, Canada
- Sainte-Justine University Hospital Ctr — Montreal, Canada (Active)
Researchers
- Principal investigator: Jacquemont, Sebastien — Sainte-Justine University Hospital Ctr
- Study coordinator: Jacquemont, Sebastien
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.