Understanding how genetic diversity evolves over time
Novel Coalescent Approaches for Studying Evolutionary Processes
This study is looking at how genetic differences happen in people and whether they are caused by helpful changes or just random chance, which could help us understand genetic disorders better and how they relate to our evolution.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-11067859 on NIH RePORTER |
What this research studies
This research investigates the evolutionary processes that shape genetic diversity by developing new statistical models and computational methods. It aims to determine whether observed genetic variations are due to adaptive changes or random factors, and to identify specific genomic regions that are under selection. By analyzing molecular data and genealogical patterns, the research seeks to provide insights into the forces influencing genetic variation across different populations and environments. Patients may benefit from a better understanding of genetic disorders and their evolutionary backgrounds.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit include individuals with genetic disorders or those interested in the genetic basis of diseases.
Not a fit: Patients with non-genetic conditions or those not affected by genetic diversity may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of genetic disorders and lead to improved strategies for diagnosis and treatment.
How similar studies have performed: Other research has successfully utilized Bayesian approaches and coalescent models to study evolutionary processes, indicating a promising foundation for this work.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: Palacios, Julia — Stanford University
- Study coordinator: Palacios, Julia
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.