Understanding how genes and environment contribute to type 2 diabetes in diverse groups

Cataloging multi-ancestry 'omic readouts of the environmental and genetic determinants of type 2 diabetes

NIH-funded research Harvard Medical School · NIH-11142512

This project aims to discover how our genes and daily surroundings work together to influence the development of type 2 diabetes in people from many different backgrounds.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionHarvard Medical School NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-11142512 on NIH RePORTER

What this research studies

We want to understand the complex connections between your environment, your genes, and biological markers in your body that lead to type 2 diabetes. By looking at factors like diet, lifestyle, and genetic makeup, we hope to find out if there are different ways these elements can cause insulin resistance or problems with insulin-producing cells. Our goal is to use blood tests to identify specific biological pathways that link your environment and genes to how your body handles sugar, ultimately leading to diabetes.

Who could benefit from this research

Good fit: This research primarily uses existing data from diverse populations, so direct patient participation in new data collection is not specified.

Not a fit: Patients not interested in contributing their health data for research or those without type 2 diabetes may not directly benefit from this specific data analysis project.

Why it matters

Potential benefit: If successful, this work could lead to a better understanding of type 2 diabetes, potentially helping to identify individuals at higher risk and develop more personalized prevention or treatment strategies.

How similar studies have performed: While individual genetic and environmental factors have been studied extensively, this project aims to combine these factors with 'omic data in a novel way across diverse populations.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Adult-Onset Diabetes MellitusAtherosclerotic Cardiovascular Disease
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.