Understanding how fear of heights affects behavior

Noradrenergic circuits in heights avoidance: an ethological, translatable threat behavior

NIH-funded research Yale University · NIH-11049195

This study is looking at how our brains react to the fear of heights, which many people experience, by changing how we see heights to learn more about how this fear affects our behavior, and it could help us understand anxiety better for everyone.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionYale University NIH-funded
Lab location1 site (New Haven, United States)
Project IDNIH-11049195 on NIH RePORTER

What this research studies

This research investigates the neural circuits involved in the fear of heights, a common anxiety trigger. By using a novel approach that manipulates visual perceptions of height, the study aims to create a controlled model to better understand how these perceptions influence behavior across different species, including humans. The research utilizes advanced techniques in circuit neuroscience to explore the connections between threat perception and behavioral responses, which could lead to new insights into anxiety and trauma-related disorders.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals experiencing anxiety disorders, particularly those with a fear of heights or related avoidance behaviors.

Not a fit: Patients who do not experience anxiety or fear of heights may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatments for anxiety disorders related to fear and avoidance behaviors.

How similar studies have performed: Previous research has shown success in using behavioral models to study anxiety, but this specific approach to height-related fear is relatively novel.

Where this research is happening

New Haven, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Anxiety Disorders
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.