Understanding how fear and gut feelings affect eating disorders

Fear, gastrointestinal distress, and interoception: Physiological and psychological mechanisms in eating disorders

NIH-funded research Ohio University Athens · NIH-10358991

This study is looking at how fear of food and gaining weight can cause stomach problems for people with eating disorders, and it wants to see how these fears affect how they feel after eating different types of food, so we can find better ways to help them stick to their treatment.

Quick facts

Grant typeR15 grant
Study typeNIH-funded research
Funding institutionOhio University Athens NIH-funded
Lab location1 site (Athens, United States)
Project IDNIH-10358991 on NIH RePORTER

What this research studies

This research investigates the relationship between fear, gastrointestinal distress, and eating disorders. It aims to understand how fear of food and weight gain can lead to physical symptoms like nausea and stomachaches, which make it hard for patients to follow treatment plans. By conducting tests where participants eat foods labeled as high or low in fat, the study will explore how these fears influence gut responses and feelings of fullness. The goal is to identify mechanisms that contribute to the maintenance of eating disorders and improve treatment adherence.

Who could benefit from this research

Good fit: Ideal candidates for this research are women in the normal weight range who are experiencing eating disorders.

Not a fit: Patients who are not experiencing eating disorders or who are outside the normal weight range may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective treatments for eating disorders by addressing the physical symptoms that hinder recovery.

How similar studies have performed: While the specific mechanisms being tested are novel, previous research has shown that addressing psychological factors can improve treatment outcomes in eating disorders.

Where this research is happening

Athens, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Mental disordersMental health disordersPsychiatric DiseasePsychiatric Disorderpsychological disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.