Understanding how epilepsy affects memory formation in the brain

Hippocampal-cortical mechanisms of altered memory consolidation in epilepsy

NIH-funded research University of California, San Francisco · NIH-11033930

This study, led by Dr. Sharon Chiang, is looking into how temporal lobe epilepsy affects memory and aims to find ways to help improve memory for people living with this condition.

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionUniversity of California, San Francisco NIH-funded
Lab location1 site (San Francisco, United States)
Project IDNIH-11033930 on NIH RePORTER

What this research studies

This research investigates the mechanisms by which epilepsy, particularly temporal lobe epilepsy, disrupts memory consolidation in the brain. The principal investigator, Dr. Sharon Chiang, aims to explore the neuronal circuits involved in memory processing and how they may be altered in individuals with epilepsy. By studying the hippocampus and its interactions with the cortex, the research seeks to identify potential interventions that could improve memory function in affected patients. The project will involve both experimental and analytical approaches to understand these complex brain processes.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults diagnosed with temporal lobe epilepsy who experience memory dysfunction.

Not a fit: Patients with epilepsy who do not experience memory issues or those with other types of epilepsy may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new treatments that enhance memory function for individuals suffering from epilepsy.

How similar studies have performed: Previous research has shown promising results in understanding memory mechanisms in epilepsy, suggesting that this approach could yield valuable insights.

Where this research is happening

San Francisco, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.