Understanding how electrical stimulation can help recover muscle function after ACL injuries
Mechanistic Assessment of NMES to Rescue Localized Neuromuscular Disruption after ACL Injury
This study is looking at how a special treatment called neuromuscular electrical stimulation can help your muscles recover better after an ACL injury, so you can get back to your normal activities faster and stronger.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Kentucky NIH-funded |
| Lab location | 1 site (Lexington, United States) |
| Project ID | NIH-10776091 on NIH RePORTER |
What this research studies
This research investigates the effects of neuromuscular electrical stimulation (NMES) on muscle recovery following anterior cruciate ligament (ACL) injuries. It aims to uncover the biological mechanisms that lead to muscle weakness and atrophy after ACL reconstruction. By analyzing molecular changes in the quadriceps muscle, the study seeks to identify how NMES can effectively target these issues and improve rehabilitation outcomes. Patients may benefit from a more tailored approach to recovery that addresses the underlying causes of muscle dysfunction.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have suffered an ACL injury and are undergoing or have undergone ACL reconstruction.
Not a fit: Patients who have not experienced an ACL injury or those with pre-existing severe muscle or neurological conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved rehabilitation strategies that enhance muscle recovery and functional outcomes for patients with ACL injuries.
How similar studies have performed: Previous research has shown promising results with NMES in muscle recovery, but this study aims to provide a more rigorous mechanistic understanding, making it a novel approach.
Where this research is happening
Lexington, United States
- University of Kentucky — Lexington, United States (Active)
Researchers
- Principal investigator: Fry, Christopher — University of Kentucky
- Study coordinator: Fry, Christopher
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.