Understanding how early life challenges affect emotional memory development

Neurocomputational Mechanisms of Affective Semantic Memory Development

NIH-funded research Columbia Univ New York Morningside · NIH-10861911

This study is looking at how tough experiences in childhood, like abuse or neglect, affect how kids and teens remember emotions, and it’s for families who want to understand how these challenges might influence mental health and help create better support for them.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionColumbia Univ New York Morningside NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-10861911 on NIH RePORTER

What this research studies

This research investigates how early-life adversities, such as abuse or neglect, impact the development of emotional memory in children and adolescents. By utilizing advanced neuroimaging techniques and computational modeling, the study aims to uncover the brain mechanisms that link these adversities to mental health outcomes. Participants may engage in assessments that involve real-world interactions, such as parent-child behaviors, to provide insights into emotional processing. The findings could help in developing targeted interventions for those affected by early-life challenges.

Who could benefit from this research

Good fit: Ideal candidates for participation include children and adolescents aged 0-21 who have experienced early-life adversities.

Not a fit: Patients who have not experienced early-life adversities or are outside the age range of 0-21 may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for preventing and treating mental health disorders in children and adolescents who have experienced early adversity.

How similar studies have performed: Previous research has shown promising results in understanding the impact of early-life adversity on mental health, suggesting that this approach could yield valuable insights.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.