Understanding how different biological responses affect sepsis treatment
Precision Medicine in Sepsis with Critical Illness
This study is looking at different ways sepsis affects people based on their immune responses, so we can find better treatments that fit each person's needs and improve care for those dealing with this serious condition.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project ID | NIH-10871866 on NIH RePORTER |
What this research studies
This research investigates the complex nature of sepsis, a critical condition that leads to high mortality rates. It aims to identify distinct biological subtypes of sepsis based on patients' immune responses, which could help tailor more effective treatments. By analyzing data from previous studies, the researchers will explore how these subtypes relate to patient outcomes and responses to therapies. The goal is to develop precision medicine approaches that target specific patient needs, improving care for those suffering from sepsis and related conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults diagnosed with sepsis or acute respiratory distress syndrome (ARDS).
Not a fit: Patients with non-critical illnesses or those not diagnosed with sepsis or ARDS may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective, personalized treatments for sepsis, potentially improving survival rates.
How similar studies have performed: Previous research has shown promise in identifying distinct phenotypes in ARDS, suggesting that similar approaches may yield valuable insights in sepsis.
Where this research is happening
Saint Louis, United States
- Washington University — Saint Louis, United States (Active)
Researchers
- Principal investigator: Sinha, Pratik — Washington University
- Study coordinator: Sinha, Pratik
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.