Understanding how diabetes affects heart disease through blood analysis
TOPMed Omics of Cardiovascular Disease in Diabetes
['FUNDING_R01'] · MASSACHUSETTS GENERAL HOSPITAL · NIH-10664855
This study is looking at how type 2 diabetes affects heart health by checking different blood markers, and it invites patients to share their health information to help discover new ways diabetes might increase the risk of heart disease.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | MASSACHUSETTS GENERAL HOSPITAL (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-10664855 on ClinicalTrials.gov |
What this research studies
This research investigates the relationship between type 2 diabetes and cardiovascular disease by analyzing various blood biomarkers. It utilizes advanced techniques such as whole genome sequencing, RNA sequencing, and metabolomics to uncover genetic and biological factors that contribute to heart disease in diabetic patients. By examining data from a large and diverse group of individuals, the study aims to identify new pathways and mechanisms that link diabetes to increased cardiovascular risk. Patients may have the opportunity to contribute their genetic and health information to help advance this important research.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with type 2 diabetes, particularly those who may be at risk for cardiovascular disease.
Not a fit: Patients without a diagnosis of type 2 diabetes or those with other unrelated cardiovascular conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention and treatment strategies for cardiovascular disease in patients with diabetes.
How similar studies have performed: Previous research has shown promise in using multi-omic approaches to understand complex diseases, indicating that this method could yield valuable insights.
Where this research is happening
BOSTON, UNITED STATES
- MASSACHUSETTS GENERAL HOSPITAL — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MEIGS, JAMES B — MASSACHUSETTS GENERAL HOSPITAL
- Study coordinator: MEIGS, JAMES B
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Atherosclerotic Cardiovascular Disease, atherosclerotic disease, atherosclerotic vascular disease