Understanding how deep brain stimulation affects brain activity
Optical voltage imaging analysis of the cellular and network mechanisms of deep brain stimulation
['FUNDING_OTHER'] · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · NIH-10558965
This study is looking into how deep brain stimulation (DBS) works to help people with neurological and psychiatric conditions by using special imaging techniques to see how it affects brain activity, which could lead to better treatments for those who need it.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-10558965 on ClinicalTrials.gov |
What this research studies
This research investigates the mechanisms behind deep brain stimulation (DBS), a treatment that uses implanted electrodes to stimulate brain tissue for various neurological and psychiatric disorders. By employing optical voltage imaging, the study aims to analyze how DBS influences cellular and network activity in the brain, which could help clarify its therapeutic effects. The research will explore different theories about how DBS works, including its potential to inhibit or excite neural activity and its role in disrupting pathological brain patterns. This comprehensive approach seeks to provide insights that could enhance the effectiveness of DBS treatments.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals suffering from neurological or psychiatric disorders who are considering or currently undergoing deep brain stimulation treatment.
Not a fit: Patients with conditions not related to neurological or psychiatric disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved deep brain stimulation therapies, offering better outcomes for patients with neurological and psychiatric disorders.
How similar studies have performed: Previous research has shown promising results in understanding the effects of deep brain stimulation, but this specific approach using optical voltage imaging is relatively novel.
Where this research is happening
BOSTON, UNITED STATES
- BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HAN, XUE — BOSTON UNIVERSITY (CHARLES RIVER CAMPUS)
- Study coordinator: HAN, XUE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Mental disorders, Mental health disorders, Psychiatric Disease, Psychiatric Disorder, psychological disorder