Understanding how daily activity affects knee joint health after ACL surgery
Official title: Steps Towards OA Prevention
Funded at University of Georgia · NIH-10906825 · Data updated 2026-11-12
This study looks at how your daily activity levels can affect the health of your knee after ACL surgery, especially in relation to the risk of developing arthritis, and it aims to find ways to keep your knee cartilage healthy.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Georgia NIH-funded |
| Lab location | 1 site (Athens, United States) |
| Project start | August 15, 2023 |
| Project end | July 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $121,473 |
| NIH project number | 5K01AR082421-02 |
| Project ID | NIH-10906825 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who have recently undergone ACL reconstruction and are experiencing low levels of daily physical activity.
✕Less likely to help
Patients who have not had ACL injuries or surgeries may not benefit from this research.
What this research studies
This research investigates the relationship between daily physical activity levels and knee joint health in individuals who have undergone anterior cruciate ligament (ACL) reconstruction. It focuses on how both excessive and insufficient mechanical loading can impact the development of osteoarthritis (OA). By using advanced imaging techniques, the study aims to identify how low daily step counts may lead to poorer cartilage health in these patients. The findings could help develop strategies to prevent OA in at-risk populations.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention strategies for osteoarthritis in individuals recovering from ACL injuries.
How similar studies have gone: Previous research has shown that understanding mechanical loading can significantly impact joint health, suggesting that this approach may yield valuable insights.
Where this research is happening
-
University of Georgia
Athens, United States Active
Researchers
- Principal investigator: Lisee, Caroline M — University of Georgia
- Study coordinator: Lisee, Caroline M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.