Understanding how cognitive control training can help treat PTSD

Identifying clinically relevant neural circuit mechanisms of cognitive control training for PTSD

NIH-funded research VA San Diego Healthcare System · NIH-10916842

This study is looking at how training your brain can help improve treatment for people with PTSD by focusing on memory and how it affects fear responses, with the goal of finding better ways to help those still struggling with symptoms.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionVA San Diego Healthcare System NIH-funded
Lab location1 site (San Diego, United States)
Project IDNIH-10916842 on NIH RePORTER

What this research studies

This research investigates the neural mechanisms involved in cognitive control training aimed at improving treatment outcomes for individuals with posttraumatic stress disorder (PTSD). It focuses on how cognitive abilities, particularly working memory, influence the process of fear extinction, which is crucial for effective therapy. By examining the relationship between cognitive control and emotional responses, the study aims to develop better therapeutic strategies for those who continue to experience PTSD symptoms despite existing treatments. Participants may undergo assessments that measure their cognitive abilities and emotional responses to various stimuli.

Who could benefit from this research

Good fit: Ideal candidates for this research are veterans and individuals experiencing persistent PTSD symptoms despite receiving standard treatments.

Not a fit: Patients who do not have PTSD or those who have not sought treatment for their symptoms may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved therapies for PTSD, enhancing recovery and quality of life for affected individuals.

How similar studies have performed: Previous research has shown promising results in using cognitive control mechanisms to enhance PTSD treatment outcomes, indicating that this approach has potential for success.

Where this research is happening

San Diego, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.