Understanding how chronic kidney disease affects brain bleeding
Mechanisms of Brain Hemorrhage in Chronic Kidney Disease
['FUNDING_R21'] · UNIVERSITY OF CALIFORNIA-IRVINE · NIH-10681454
This study is looking at how chronic kidney disease might increase the risk of serious brain bleeding, and it aims to find specific signs in brain scans that could help doctors understand how severe the bleeding might be for patients with kidney issues.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA-IRVINE (nih funded) |
| Locations | 1 site (IRVINE, UNITED STATES) |
| Trial ID | NIH-10681454 on ClinicalTrials.gov |
What this research studies
This research investigates the link between chronic kidney disease (CKD) and intracerebral hemorrhage (ICH), a serious type of brain bleeding. It aims to identify specific imaging biomarkers, such as intracranial arterial calcification and cerebral microbleeds, that may predict the severity of ICH in patients with CKD. By analyzing a large database of ICH patients and using advanced imaging techniques, the study seeks to uncover the mechanisms by which CKD increases the risk of brain hemorrhage. This could lead to better risk assessment and management strategies for affected patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with chronic kidney disease who may also be at risk for intracerebral hemorrhage.
Not a fit: Patients without chronic kidney disease or those who have not experienced brain hemorrhage may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for patients with chronic kidney disease at risk for brain hemorrhage.
How similar studies have performed: Previous research has indicated a correlation between chronic kidney disease and increased risk of brain hemorrhage, suggesting that this study builds on established findings.
Where this research is happening
IRVINE, UNITED STATES
- UNIVERSITY OF CALIFORNIA-IRVINE — IRVINE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: CHANG, PETER — UNIVERSITY OF CALIFORNIA-IRVINE
- Study coordinator: CHANG, PETER
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Kidney Diseases, Renal Disease, kidney disorder, renal disorder, Chronic Renal Disease