Understanding how Chlamydia bacteria develop and cause infections
Host-pathogen interactions controlling Chlamydia developmental cycle
['FUNDING_R01'] · UNIVERSITY OF VIRGINIA · NIH-10656443
This study is looking at how the Chlamydia bacteria change and grow inside our cells, with the hope of finding new ways to treat or prevent infections for people affected by this common sexually transmitted infection.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF VIRGINIA (nih funded) |
| Locations | 1 site (CHARLOTTESVILLE, UNITED STATES) |
| Trial ID | NIH-10656443 on ClinicalTrials.gov |
What this research studies
This research investigates the developmental cycle of Chlamydia trachomatis, a leading cause of sexually transmitted infections. It focuses on how the bacteria transition between different forms within host cells and how this process contributes to disease. By studying a specific protein involved in this cycle, the researchers aim to uncover mechanisms that could lead to new treatments or prevention strategies. The approach includes advanced techniques in cell biology and genetics to analyze the interactions between the bacteria and host cells.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who are at risk of or currently infected with Chlamydia trachomatis.
Not a fit: Patients who are not sexually active or those who have no history of Chlamydia infections may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments or preventive measures for Chlamydia infections, potentially reducing long-term health complications.
How similar studies have performed: Previous research has shown promise in understanding bacterial infections through similar approaches, but this specific investigation into Chlamydia's developmental cycle is relatively novel.
Where this research is happening
CHARLOTTESVILLE, UNITED STATES
- UNIVERSITY OF VIRGINIA — CHARLOTTESVILLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: DERRE, ISABELLE — UNIVERSITY OF VIRGINIA
- Study coordinator: DERRE, ISABELLE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Bacterial Infections, bacteria infection, bacterial disease