Understanding how children's brains respond to sensory overload

Neural mechanisms of sensory over-responsivity in children with and without ASD

['FUNDING_OTHER'] · WASHINGTON UNIVERSITY · NIH-11137322

This study is looking at why some children with autism have strong negative reactions to everyday sounds, sights, and touches, and it hopes to find ways to help them feel better and enjoy life more.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorWASHINGTON UNIVERSITY (nih funded)
Locations1 site (SAINT LOUIS, UNITED STATES)
Trial IDNIH-11137322 on ClinicalTrials.gov

What this research studies

This research investigates sensory over-responsivity (SOR) in children, particularly those with autism spectrum disorder (ASD). It aims to identify the neural mechanisms that lead to strong negative reactions to everyday sensory stimuli, which can cause significant distress and impairment in social and developmental functioning. By studying how typical sensory processing occurs in the brain, the research seeks to uncover what goes wrong in children with SOR, potentially leading to better interventions. The findings could help improve the quality of life for affected children and their families.

Who could benefit from this research

Good fit: Ideal candidates for this research are children aged 0-11 years who exhibit sensory over-responsivity, particularly those diagnosed with autism spectrum disorder.

Not a fit: Children who do not experience sensory over-responsivity or those outside the age range of 0-11 years may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective treatments for children suffering from sensory over-responsivity, improving their daily experiences and overall well-being.

How similar studies have performed: Previous research has shown promise in understanding sensory processing in typical populations, suggesting that this approach could yield valuable insights into sensory over-responsivity.

Where this research is happening

SAINT LOUIS, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Anxiety Disorders, Autistic Disorder

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.