Understanding how changes in DNA methylation relate to various diseases
Pan-disease characterization of DNA methylation dysregulation
This study is looking at how changes in DNA can affect diseases like cancer and autoimmune disorders, and it’s for anyone interested in understanding how these changes might help doctors find better ways to diagnose and treat these conditions early on.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Utah NIH-funded |
| Lab location | 1 site (Salt Lake City, United States) |
| Project ID | NIH-11055414 on NIH RePORTER |
What this research studies
This research investigates the role of DNA methylation, an important epigenetic marker, in various diseases such as cancer and autoimmune disorders. It aims to identify specific genomic elements that contribute to methylation dysregulation, which can indicate disease severity and treatment response. By developing computational algorithms, the research will analyze patient samples across multiple diseases to uncover common origins of these conditions. This approach may lead to new diagnostic and therapeutic strategies for early intervention.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with cancer, autoimmune diseases, or other conditions associated with DNA methylation dysregulation.
Not a fit: Patients with conditions unrelated to DNA methylation dysregulation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic tools and early treatment options for patients with various diseases linked to DNA methylation changes.
How similar studies have performed: Previous research has shown promising results in understanding the role of DNA methylation in disease, indicating that this approach has potential for significant findings.
Where this research is happening
Salt Lake City, United States
- University of Utah — Salt Lake City, United States (Active)
Researchers
- Principal investigator: Clement, Kendell — University of Utah
- Study coordinator: Clement, Kendell
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.