Understanding how certain proteins help cells respond to stress
Discovery of Novel Mechanisms of Action of Ubiquitin-Like Proteins in Cellular Stress Pathways
This study is looking at how certain proteins help our cells handle stress, like during infections or diseases that affect the brain, to find new ways to keep our cells healthy and possibly develop better treatments.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | National Jewish Health NIH-funded |
| Lab location | 1 site (Denver, United States) |
| Project ID | NIH-11012730 on NIH RePORTER |
What this research studies
This research investigates the role of ubiquitin-like proteins in cellular stress responses, which are crucial for maintaining cell health. By using advanced proteomics techniques, the study aims to uncover how these proteins modify other cellular proteins during stress conditions, such as infections or neurodegenerative diseases. The findings could reveal new insights into how cells manage stress and potentially lead to new therapeutic strategies for related diseases.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals suffering from cancer, autoimmune diseases, or neurodegenerative disorders.
Not a fit: Patients with conditions unrelated to cellular stress responses may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for diseases like cancer and neurodegenerative disorders by enhancing our understanding of cellular stress responses.
How similar studies have performed: Other research has shown promising results in understanding cellular stress responses, indicating that this approach could yield valuable insights.
Where this research is happening
Denver, United States
- National Jewish Health — Denver, United States (Active)
Researchers
- Principal investigator: Radoshevich, Lilliana — National Jewish Health
- Study coordinator: Radoshevich, Lilliana
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.