Understanding how certain proteins affect inflammation
The role of intermediate filaments during inflammation
This study is looking at how certain proteins in our cells help manage inflammation, especially in white blood cells that fight infections, to find new ways to improve how our bodies handle inflammation.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project ID | NIH-11034383 on NIH RePORTER |
What this research studies
This research investigates the role of intermediate filaments, which are important proteins found in nearly every cell, during inflammation. It aims to uncover how these proteins interact with other cellular components and contribute to the inflammatory response, particularly in neutrophils, a type of white blood cell. By using advanced cellular models, the research will explore the molecular mechanisms that regulate these proteins and their impact on inflammation, especially during bacterial infections. This could lead to new insights into how inflammation is managed in the body.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing inflammatory conditions or bacterial infections.
Not a fit: Patients with non-inflammatory conditions or those not affected by bacterial infections may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for inflammatory conditions and bacterial infections.
How similar studies have performed: Previous research has shown promising results in understanding the role of intermediate filaments in cellular processes, suggesting that this approach could yield valuable insights.
Where this research is happening
Aurora, UNITED STATES
- University of Colorado Denver — Aurora, United States (Active)
Researchers
- Principal investigator: Russo, Brian — University of Colorado Denver
- Study coordinator: Russo, Brian
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.