Understanding how certain immune cells help heal lung injuries
Defining a stromal niche for type 2-like lung regulatory T cells
['FUNDING_FELLOWSHIP'] · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · NIH-10908711
This study is looking at how special immune cells in the lungs help heal injuries and breathing problems, and it aims to find out where these cells work best and how they team up with other cells, which could lead to new treatments for people with serious lung issues.
Quick facts
| Phase | ['FUNDING_FELLOWSHIP'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA, SAN FRANCISCO (nih funded) |
| Locations | 1 site (SAN FRANCISCO, UNITED STATES) |
| Trial ID | NIH-10908711 on ClinicalTrials.gov |
What this research studies
This research investigates the role of regulatory T cells in the lungs, particularly how they contribute to healing during acute lung injuries and respiratory distress. The study focuses on identifying the specific environment, or 'niche', where these immune cells operate and how they interact with other cells in the lung tissue. By using advanced imaging techniques, researchers aim to uncover the mechanisms that allow these T cells to promote lung regeneration. This knowledge could lead to new therapeutic strategies for patients suffering from severe lung conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals experiencing acute lung injuries or acute respiratory distress syndrome.
Not a fit: Patients with chronic lung diseases or those not currently experiencing acute lung injuries may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for patients with acute lung injuries and respiratory distress, potentially enhancing recovery and reducing mortality.
How similar studies have performed: Previous research has shown promising results in understanding the role of immune cells in tissue repair, suggesting that this approach could yield valuable insights.
Where this research is happening
SAN FRANCISCO, UNITED STATES
- UNIVERSITY OF CALIFORNIA, SAN FRANCISCO — SAN FRANCISCO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: CHANG, ANTHONY — UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
- Study coordinator: CHANG, ANTHONY
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acute Lung Injury, Acute Pulmonary Injury, Acute Respiratory Distress Syndrome, Adult Respiratory Distress Syndrome