Understanding how certain bacteria inhibit each other's growth
Structure and function of Burkholderia contact-dependent growth inhibition (CDI) systems
['FUNDING_R01'] · UNIVERSITY OF KENTUCKY · NIH-10896337
This study is looking at how certain bacteria can stop other bacteria from growing, which could help us find new ways to treat tough infections with better antibiotics or vaccines.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF KENTUCKY (nih funded) |
| Locations | 1 site (LEXINGTON, UNITED STATES) |
| Trial ID | NIH-10896337 on ClinicalTrials.gov |
What this research studies
This research investigates the mechanisms by which some bacteria can inhibit the growth of neighboring bacteria through a process called contact-dependent growth inhibition (CDI). By studying the proteins involved in this interaction, the research aims to uncover how bacteria communicate and compete with each other. The approach includes examining the molecular functions of these proteins and their potential therapeutic applications, such as developing new antibiotics or vaccines. Patients may benefit from this research as it could lead to innovative treatments for bacterial infections that are currently difficult to manage.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from bacterial infections, particularly those caused by antibiotic-resistant strains.
Not a fit: Patients with viral infections or non-bacterial diseases may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that effectively treat or prevent bacterial infections.
How similar studies have performed: While the concept of bacterial competition is established, the specific mechanisms of CDI systems are less explored, making this research a novel approach.
Where this research is happening
LEXINGTON, UNITED STATES
- UNIVERSITY OF KENTUCKY — LEXINGTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: GARCIA, ERIN C — UNIVERSITY OF KENTUCKY
- Study coordinator: GARCIA, ERIN C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Bacterial Infections