Understanding how cells move in three dimensions
Official title: Deconstructing fast amoeboid cell migration
Funded at State University New York Stony Brook · NIH-11020628 · Data updated 2026-11-12
This study is looking at how cells move in 3D spaces, especially how they can quickly change shape and travel without the usual structures, which is important for understanding conditions like cancer where cell movement can affect disease progression.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | State University New York Stony Brook NIH-funded |
| Lab location | 1 site (Stony Brook, United States) |
| Project start | September 16, 2024 |
| Project end | July 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $395,387 |
| NIH project number | 1R35GM157022-01 |
| Project ID | NIH-11020628 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with cancers or conditions where abnormal cell migration is a factor.
✕Less likely to help
Patients with non-malignant conditions unrelated to cell migration may not benefit from this research.
What this research studies
This research investigates the mechanisms behind how cells migrate in three-dimensional environments, particularly focusing on a type of movement known as fast amoeboid migration. By studying how cells can change shape and move without traditional structures, the research aims to uncover the molecular processes that enable this behavior. This knowledge is crucial as it relates to various health conditions, especially cancer, where cell movement can lead to disease progression. The approach involves advanced techniques to observe and manipulate cell migration in live models.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for treating diseases like cancer by targeting the mechanisms of cell movement.
How similar studies have gone: Previous research has shown promising results in understanding cell migration, but this specific focus on fast amoeboid migration is relatively novel.
Where this research is happening
-
State University New York Stony Brook
Stony Brook, United States Active
Researchers
- Principal investigator: Lin, Benjamin C — State University New York Stony Brook
- Study coordinator: Lin, Benjamin C
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.