Understanding how cells move in three dimensions
Deconstructing fast amoeboid cell migration
This study is looking at how cells move in 3D spaces, especially how they can quickly change shape and travel without the usual structures, which is important for understanding conditions like cancer where cell movement can affect disease progression.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | State University New York Stony Brook NIH-funded |
| Lab location | 1 site (Stony Brook, United States) |
| Project ID | NIH-11020628 on NIH RePORTER |
What this research studies
This research investigates the mechanisms behind how cells migrate in three-dimensional environments, particularly focusing on a type of movement known as fast amoeboid migration. By studying how cells can change shape and move without traditional structures, the research aims to uncover the molecular processes that enable this behavior. This knowledge is crucial as it relates to various health conditions, especially cancer, where cell movement can lead to disease progression. The approach involves advanced techniques to observe and manipulate cell migration in live models.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with cancers or conditions where abnormal cell migration is a factor.
Not a fit: Patients with non-malignant conditions unrelated to cell migration may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for treating diseases like cancer by targeting the mechanisms of cell movement.
How similar studies have performed: Previous research has shown promising results in understanding cell migration, but this specific focus on fast amoeboid migration is relatively novel.
Where this research is happening
Stony Brook, United States
- State University New York Stony Brook — Stony Brook, United States (Active)
Researchers
- Principal investigator: Lin, Benjamin C — State University New York Stony Brook
- Study coordinator: Lin, Benjamin C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.