Understanding how cells establish their orientation during development
Symmetry Breaking in Cell Assemblies
This study looks at how cells in developing organisms, like the tiny worm C. elegans, learn to organize themselves properly, which is important for growth, by observing how they break symmetry and work together.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-11089291 on NIH RePORTER |
What this research studies
This research investigates how individual cells in multicellular organisms establish their polarity, which is crucial for proper development. Using the C. elegans embryo as a model, the research aims to identify patterns of symmetry breaking events that lead to coordinated cell polarization. The approach involves imaging and analyzing molecular assemblies that contribute to this process, focusing on how these events are interconnected across tissues. By understanding these mechanisms, the research seeks to shed light on the fundamental processes that guide cell behavior during development.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research would include individuals with genetic conditions related to cell adhesion and polarity.
Not a fit: Patients with conditions unrelated to cellular development or polarity may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of developmental processes and potentially inform treatments for birth defects and other developmental disorders.
How similar studies have performed: Other research has shown success in understanding cell polarity and symmetry breaking in model organisms, indicating that this approach has a solid foundation in existing scientific knowledge.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: Devitt, Caitlin C — Stanford University
- Study coordinator: Devitt, Caitlin C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.