Understanding how cells control their size and shape
Mechanisms controlling cell size and shape
This study looks at how tiny building blocks in our cells grow and divide, using a type of yeast to understand the process better, and it hopes to find new ways to help treat diseases like cancer.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Dartmouth College NIH-funded |
| Lab location | 1 site (Hanover, United States) |
| Project ID | NIH-11171251 on NIH RePORTER |
What this research studies
This research investigates the molecular and cellular mechanisms that determine the size and shape of cells, which are crucial for normal cell function. By using the fission yeast S. pombe as a model organism, the research aims to uncover how specific proteins and signaling pathways regulate cell growth and division. The approach combines various techniques, including genetics and live-cell imaging, to explore how defects in these processes can lead to diseases like cancer. The findings could help identify new therapeutic targets for treatment.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with cancers or other diseases linked to cell growth and division abnormalities.
Not a fit: Patients with conditions unrelated to cell size and shape regulation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for treating diseases associated with abnormal cell size and shape, such as cancer.
How similar studies have performed: Other research has shown success in understanding cell cycle regulation and its implications for cancer treatment, making this approach promising.
Where this research is happening
Hanover, United States
- Dartmouth College — Hanover, United States (Active)
Researchers
- Principal investigator: Moseley, James B — Dartmouth College
- Study coordinator: Moseley, James B
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.