Understanding how cells control their size and shape
Official title: Mechanisms controlling cell size and shape
Funded at Dartmouth College · NIH-11171251 · Data updated 2026-11-12
This study looks at how tiny building blocks in our cells grow and divide, using a type of yeast to understand the process better, and it hopes to find new ways to help treat diseases like cancer.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Dartmouth College NIH-funded |
| Lab location | 1 site (Hanover, United States) |
| Project start | September 25, 2023 |
| Project end | August 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $29,969 |
| NIH project number | 3R35GM149248-02S1 |
| Project ID | NIH-11171251 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with cancers or other diseases linked to cell growth and division abnormalities.
✕Less likely to help
Patients with conditions unrelated to cell size and shape regulation may not benefit from this research.
What this research studies
This research investigates the molecular and cellular mechanisms that determine the size and shape of cells, which are crucial for normal cell function. By using the fission yeast S. pombe as a model organism, the research aims to uncover how specific proteins and signaling pathways regulate cell growth and division. The approach combines various techniques, including genetics and live-cell imaging, to explore how defects in these processes can lead to diseases like cancer. The findings could help identify new therapeutic targets for treatment.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for treating diseases associated with abnormal cell size and shape, such as cancer.
How similar studies have gone: Other research has shown success in understanding cell cycle regulation and its implications for cancer treatment, making this approach promising.
Where this research is happening
-
Dartmouth College
Hanover, United States Active
Researchers
- Principal investigator: Moseley, James B — Dartmouth College
- Study coordinator: Moseley, James B
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.