Understanding how cells communicate in vitiligo
Cell-Cell Communications and Tissue Memory in Vitiligo
['FUNDING_OTHER'] · UNIV OF MASSACHUSETTS MED SCH WORCESTER · NIH-10868483
This study is looking at how skin cells talk to each other and how that communication goes wrong in vitiligo, a condition that causes skin to lose its color, with the hope of finding new ways to treat it.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIV OF MASSACHUSETTS MED SCH WORCESTER (nih funded) |
| Locations | 1 site (WORCESTER, UNITED STATES) |
| Trial ID | NIH-10868483 on ClinicalTrials.gov |
What this research studies
This research investigates the communication between cells in the skin, particularly focusing on how these interactions are disrupted in vitiligo, an autoimmune disease that causes loss of skin pigment. By utilizing advanced techniques like single cell RNA sequencing, the study aims to map out the signaling pathways involved in vitiligo and identify the molecules that are altered in affected skin. This could lead to a better understanding of the disease and the development of new treatments that target these communication pathways. The research emphasizes the importance of cell-to-cell interactions in maintaining skin health and how their disruption can lead to autoimmune conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with vitiligo, particularly those experiencing significant skin changes.
Not a fit: Patients with vitiligo who are not actively seeking treatment or those with other unrelated skin conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for vitiligo, enhancing the quality of life for patients affected by this condition.
How similar studies have performed: Previous research has shown promise in understanding autoimmune diseases through cell communication studies, suggesting that this approach could yield valuable insights.
Where this research is happening
WORCESTER, UNITED STATES
- UNIV OF MASSACHUSETTS MED SCH WORCESTER — WORCESTER, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: GARBER, MANUEL — UNIV OF MASSACHUSETTS MED SCH WORCESTER
- Study coordinator: GARBER, MANUEL
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Autoimmune Diseases