Understanding how CD7 affects T cell function
Unmasking the Immunomodulatory Roles of CD7 Signaling
['FUNDING_R01'] · UNIVERSITY OF UTAH · NIH-10891386
This study is looking at how a protein called CD7 helps T cells, which are important for fighting infections and diseases, do their job better or worse, and it could lead to new treatments for conditions like cancer and autoimmune diseases.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF UTAH (nih funded) |
| Locations | 1 site (SALT LAKE CITY, UNITED STATES) |
| Trial ID | NIH-10891386 on ClinicalTrials.gov |
What this research studies
This research investigates the role of CD7 in T cells, focusing on how it influences T cell receptor signaling and overall immune responses. The study aims to uncover the mechanisms by which CD7 supports T cell differentiation during infections, cancers, and autoimmune diseases. By analyzing T cell behavior at various biological levels, the research seeks to determine how targeting CD7 could enhance or suppress T cell activity, potentially leading to new therapeutic strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with viral infections, cancers, or autoimmune diseases who may benefit from enhanced T cell function.
Not a fit: Patients with conditions unrelated to T cell function or those who do not have immune system involvement may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that improve immune responses in patients with infections, cancers, or autoimmune diseases.
How similar studies have performed: Previous research has shown promising results in targeting similar immunomodulatory pathways, suggesting potential for success in this novel approach.
Where this research is happening
SALT LAKE CITY, UNITED STATES
- UNIVERSITY OF UTAH — SALT LAKE CITY, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LO, WAN-LIN — UNIVERSITY OF UTAH
- Study coordinator: LO, WAN-LIN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Autoimmune Diseases