Understanding how care decisions affect outcomes for patients with breathing problems and sepsis

Identifying patient subgroups and processes of care that cause outcome differences following ICU vs. ward triage among patients with acute respiratory failure and sepsis

['FUNDING_R01'] · UNIVERSITY OF PENNSYLVANIA · NIH-11160556

This project looks at hospital records to understand how decisions about where patients with severe breathing issues and sepsis receive care affect their recovery.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF PENNSYLVANIA (nih funded)
Locations1 site (PHILADELPHIA, UNITED STATES)
Trial IDNIH-11160556 on ClinicalTrials.gov

What this research studies

We know that where patients with acute respiratory failure and sepsis are treated—either in an intensive care unit (ICU) or a regular hospital ward—can greatly impact their health. This project will analyze a vast amount of patient health record data from many hospitalizations to identify specific groups of patients and care practices that lead to better or worse outcomes. By understanding these differences, we hope to improve how these critical decisions are made. Our goal is to help ensure patients receive the most appropriate care for their condition.

Who could benefit from this research

Good fit: This project focuses on understanding past care for patients who have experienced acute respiratory failure and sepsis.

Not a fit: Patients who have not experienced acute respiratory failure or sepsis would not directly benefit from this specific research.

Why it matters

Potential benefit: If successful, this work could lead to more informed decisions about where patients with acute respiratory failure and sepsis receive care, potentially improving their chances of recovery and reducing complications.

How similar studies have performed: Prior work by this team has already shown that initial care decisions significantly impact patient outcomes, suggesting a strong foundation for this expanded analysis.

Where this research is happening

PHILADELPHIA, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Acute Respiratory Distress Syndrome

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.