Understanding how cancer becomes resistant to treatment
DYNAMIC MOLECULAR EVOLUTION OF TREATMENT RESISTANT CANCER
['FUNDING_OTHER'] · UNIVERSITY OF WISCONSIN-MADISON · NIH-11134807
This study is looking at how some cancers become hard to treat by using a new blood test that helps us understand changes in the cancer over time, so we can find better ways to help patients like you.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF WISCONSIN-MADISON (nih funded) |
| Locations | 1 site (MADISON, UNITED STATES) |
| Trial ID | NIH-11134807 on ClinicalTrials.gov |
What this research studies
This research investigates the mechanisms behind treatment-resistant cancer by utilizing a novel 'liquid biopsy' technique. Instead of relying on invasive tissue samples, the study collects molecular information from blood samples provided by patients. This approach allows researchers to monitor how cancer evolves and develops resistance over time, potentially leading to earlier interventions and more effective treatment strategies. The goal is to improve patient outcomes by identifying resistance patterns and adjusting treatments accordingly.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients with advanced cancer who are undergoing treatment and providing blood samples for routine tests.
Not a fit: Patients with early-stage cancer or those not receiving systemic treatments may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for patients with advanced cancer by identifying resistance early and adapting therapies.
How similar studies have performed: Other research has shown promise in using liquid biopsies to monitor cancer evolution, indicating that this approach could be effective.
Where this research is happening
MADISON, UNITED STATES
- UNIVERSITY OF WISCONSIN-MADISON — MADISON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ZHAO, SHUANG — UNIVERSITY OF WISCONSIN-MADISON
- Study coordinator: ZHAO, SHUANG
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Advanced Cancer, Cancers