Understanding how calcium channels work in cells
Molecular and cellular mechanisms of store-operated calcium channels
['FUNDING_OTHER'] · STANFORD UNIVERSITY · NIH-11066514
This study is looking at how certain channels in our cells help control calcium signals, which are important for things like immune responses and muscle function, to better understand how these processes work and how they might be linked to different health issues.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | STANFORD UNIVERSITY (nih funded) |
| Locations | 1 site (STANFORD, UNITED STATES) |
| Trial ID | NIH-11066514 on ClinicalTrials.gov |
What this research studies
This research investigates the mechanisms by which store-operated calcium channels (SOCs) function in cells, focusing on how calcium signals are generated and regulated. It explores the interactions between proteins that control calcium entry, particularly in immune cells and muscle tissues. By examining the dynamics of junctions between the endoplasmic reticulum and the plasma membrane, the research aims to uncover how these processes influence various physiological functions and disease states. The study employs advanced molecular and cellular techniques to analyze these critical pathways.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with autoimmune diseases or conditions related to calcium signaling dysfunction.
Not a fit: Patients with conditions unrelated to calcium signaling or autoimmune disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for autoimmune diseases and other conditions linked to calcium signaling abnormalities.
How similar studies have performed: Previous research has shown promising results in understanding calcium signaling pathways, indicating that this approach could yield valuable insights.
Where this research is happening
STANFORD, UNITED STATES
- STANFORD UNIVERSITY — STANFORD, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LEWIS, RICHARD S — STANFORD UNIVERSITY
- Study coordinator: LEWIS, RICHARD S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Autoimmune Diseases, autoimmune disorder, autoimmunity disease