Understanding how brain waves interact in health and disease
Cross-frequency coupling: its role in brain function and dysfunction
This study is looking at how different parts of the brain work together when people with drug-resistant epilepsy try to remember things, using advanced technology to better understand both memory and epilepsy.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Georgetown University NIH-funded |
| Lab location | 1 site (Washington, United States) |
| Project ID | NIH-10008042 on NIH RePORTER |
What this research studies
This research investigates the interactions between different brain regions during memory tasks and epilepsy by analyzing existing data from patients with drug-resistant epilepsy. Using advanced machine learning techniques, specifically deep learning neural networks, the study aims to uncover the mechanisms behind memory formation and the pathological processes of epilepsy. By examining intracranial EEG recordings, the research seeks to identify how brain oscillations influence communication within and between brain networks. This innovative approach leverages large datasets to enhance our understanding of brain dynamics over time.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients with drug-resistant epilepsy who have undergone presurgical evaluations and have intracranial EEG data available.
Not a fit: Patients with well-controlled epilepsy or those who do not have access to intracranial EEG data may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for epilepsy and better strategies for enhancing memory function.
How similar studies have performed: Other research has shown promising results using similar machine learning approaches to analyze brain data, indicating potential for success in this area.
Where this research is happening
Washington, United States
- Georgetown University — Washington, United States (Active)
Researchers
- Principal investigator: Medvedev, Andrei V — Georgetown University
- Study coordinator: Medvedev, Andrei V
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.