Understanding how brain tumors interact with nerve cells
Decoding hyperexcitability in malignant glioma
This study is looking at how aggressive brain tumors called malignant gliomas interact with nearby nerve cells to find new ways to improve treatment for patients like you.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-10949100 on NIH RePORTER |
What this research studies
This research investigates the mechanisms behind malignant gliomas, a type of aggressive brain tumor, and their interactions with surrounding nerve cells. By exploring how glioma cells communicate with non-tumor neurons, the study aims to uncover new therapeutic targets that could improve treatment outcomes. The research utilizes advanced techniques, including mouse models, to analyze the role of specific proteins in tumor growth and maintenance. Patients may benefit from insights that could lead to innovative treatment strategies for glioblastoma and other malignant gliomas.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with malignant gliomas, particularly those with glioblastoma.
Not a fit: Patients with non-malignant brain tumors or those without brain tumors may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that significantly improve survival rates for patients with malignant gliomas.
How similar studies have performed: Other research in cancer neuroscience has shown promise in understanding tumor-neuron interactions, suggesting that this approach could yield valuable insights.
Where this research is happening
Houston, United States
- Baylor College of Medicine — Houston, United States (Active)
Researchers
- Principal investigator: Curry, Rachel Naomi — Baylor College of Medicine
- Study coordinator: Curry, Rachel Naomi
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.