NIH-funded research R21 grant

Understanding how brain signals affect hearing in noisy environments

Official title: Olivocochlear Efferent Function: Associations with Hearing in Noise and Listening Effort

Funded at University of Illinois at Urbana-Champaign · NIH-11017776 · Data updated 2026-11-12

This study is looking at how a part of the brain helps people hear speech better in noisy places, especially for those who find it hard to understand conversations when there's background noise, even if their hearing tests are normal.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of Illinois at Urbana-Champaign
NIH-funded
Lab location1 site (Champaign, United States)
Project startFebruary 1, 2024
Project endJanuary 31, 2027
Funding year2025
Award (this year)$190,302
NIH project number5R21DC020258-02
Project IDNIH-11017776 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are adults aged 21 and older who experience difficulties hearing speech in background noise.

Less likely to help

Patients who do not have any hearing difficulties or those with significant hearing loss may not benefit from this research.

What this research studies

This research investigates how the brain's olivocochlear system influences the ability to hear speech in noisy settings. It aims to understand the mechanisms behind difficulties that many adults face when trying to listen in background noise, despite having normal hearing tests. By studying two groups of adults—those who report challenges with hearing in noise and those who do not—the research will explore the role of the medial olivocochlear reflex in reducing background noise interference. The findings could lead to better diagnostic and treatment options for individuals struggling with these hearing challenges.

Why it matters

Potential benefit: If successful, this research could lead to improved diagnostic methods and treatments for adults who have trouble hearing in noisy environments.

How similar studies have gone: Previous studies have shown mixed results regarding the olivocochlear reflex and its impact on hearing in noise, indicating that this research could provide valuable new insights.

Where this research is happening

  • University of Illinois at Urbana-Champaign
    Champaign, United States
    Active

Researchers

  • Principal investigator: Mertes, Ian B. — University of Illinois at Urbana-Champaign
  • Study coordinator: Mertes, Ian B.

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.