Understanding how brain regions affect communication and decision-making.

Semantic Systems

NIH-funded research University of South Carolina at Columbia · NIH-10837757

This study looks at how our brains understand things like objects and social interactions, especially focusing on a part of the brain that can cause problems for people with certain neurological and psychiatric conditions, with the goal of finding better ways to help them communicate and make decisions.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of South Carolina at Columbia NIH-funded
Lab location1 site (Columbia, United States)
Project IDNIH-10837757 on NIH RePORTER

What this research studies

This research investigates how conceptual knowledge, which includes understanding objects, actions, and social interactions, is processed in the brain. It focuses on the anterior temporal lobe, a key area involved in these functions, and examines how impairments in this region can affect individuals with neurological and psychiatric disorders. By studying the neural basis of these impairments, the research aims to develop better treatments and rehabilitation strategies for affected patients. The findings could lead to improved communication and decision-making abilities for those with related conditions.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals diagnosed with neurological or psychiatric disorders such as stroke with aphasia, dementia, temporal lobe epilepsy, schizophrenia, or autism.

Not a fit: Patients without any cognitive or communication impairments may not receive direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to enhanced therapies and rehabilitation techniques for patients with communication and cognitive impairments.

How similar studies have performed: Previous research has shown promising results in understanding the neural basis of communication and decision-making, indicating that this approach has potential for success.

Where this research is happening

Columbia, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Mental health disordersPsychiatric DiseasePsychiatric Disorderpsychological disorderMental disorders
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.