Understanding how brain circuits support language and memory.
Official title: Laminar Circuit Motifs for Working Memory and Language Combinatorics: From Cells to Systems
Funded at University of Iowa · NIH-10934028 · Data updated 2026-11-12
This study is looking at how our brains help us understand and use language by working with patients who are having brain surgery, and it hopes to learn more about how these brain functions can be affected in people with neurological disorders.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Iowa NIH-funded |
| Lab location | 1 site (Iowa City, United States) |
| Project start | September 18, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $1,217,318 |
| NIH project number | 1U01NS137991-01 |
| Project ID | NIH-10934028 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation are patients undergoing neurosurgery who have language or memory impairments.
✕Less likely to help
Patients without neurological disorders or those not undergoing neurosurgery may not benefit from this research.
What this research studies
This research investigates the neural mechanisms that underlie language and working memory by examining brain circuits in patients undergoing neurosurgery. Using advanced techniques, including high-density recordings and genomic analyses, the study aims to uncover how different layers of the brain contribute to our ability to combine words and manipulate thoughts. By involving up to 100 patients, the research seeks to gather valuable data that can enhance our understanding of cognitive functions and their disruptions in neurological disorders.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for language and memory disorders.
How similar studies have gone: Other research has shown promise in understanding brain functions related to language and memory, but this approach aims to provide novel insights through advanced methodologies.
Where this research is happening
-
University of Iowa
Iowa City, United States Active
Researchers
- Principal investigator: Petkov, Christopher I — University of Iowa
- Study coordinator: Petkov, Christopher I
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.