Understanding how brain circuits control arm movements

Synaptic circuit organization of motor cortex

NIH-funded research Northwestern University at Chicago · NIH-10999422

This study is looking at how the brain helps us move our arms and hands to do everyday tasks, and it aims to find ways to improve treatments for people who have trouble with movement.

Quick facts

Grant typeR37 grant
Study typeNIH-funded research
Funding institutionNorthwestern University at Chicago NIH-funded
Lab location1 site (Chicago, United States)
Project IDNIH-10999422 on NIH RePORTER

What this research studies

This research investigates the brain circuits involved in controlling goal-directed movements of the arms and hands, which are crucial for daily activities. By studying the synaptic organization of the primary motor cortex, the research aims to uncover the mechanisms behind motor planning and execution. The approach includes examining the communication between different brain areas that contribute to these movements, particularly focusing on how sensory feedback influences motor actions. This foundational neuroscience work could lead to better treatments for disabilities caused by motor dysfunction.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals experiencing motor dysfunction affecting their ability to perform daily living activities.

Not a fit: Patients with intact motor function or those whose disabilities are not related to cortical dysfunction may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved therapies for individuals with motor disabilities, enhancing their ability to perform daily activities.

How similar studies have performed: Previous research has shown promise in understanding motor control circuits, suggesting that this approach could yield valuable insights.

Where this research is happening

Chicago, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.