Understanding how brain circuits control arm movements
Official title: Synaptic circuit organization of motor cortex
Funded at Northwestern University at Chicago · NIH-10999422 · Data updated 2026-11-12
This study is looking at how the brain helps us move our arms and hands to do everyday tasks, and it aims to find ways to improve treatments for people who have trouble with movement.
Quick facts
| Grant type | R37 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Northwestern University at Chicago NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project start | December 15, 2023 |
| Project end | November 30, 2027 |
| Funding year | 2025 |
| Award (this year) | $511,142 |
| NIH project number | 5R37NS061963-17 |
| Project ID | NIH-10999422 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals experiencing motor dysfunction affecting their ability to perform daily living activities.
✕Less likely to help
Patients with intact motor function or those whose disabilities are not related to cortical dysfunction may not benefit from this research.
What this research studies
This research investigates the brain circuits involved in controlling goal-directed movements of the arms and hands, which are crucial for daily activities. By studying the synaptic organization of the primary motor cortex, the research aims to uncover the mechanisms behind motor planning and execution. The approach includes examining the communication between different brain areas that contribute to these movements, particularly focusing on how sensory feedback influences motor actions. This foundational neuroscience work could lead to better treatments for disabilities caused by motor dysfunction.
Why it matters
Potential benefit: If successful, this research could lead to improved therapies for individuals with motor disabilities, enhancing their ability to perform daily activities.
How similar studies have gone: Previous research has shown promise in understanding motor control circuits, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Northwestern University at Chicago
Chicago, United States Active
Researchers
- Principal investigator: Shepherd, Gordon M — Northwestern University at Chicago
- Study coordinator: Shepherd, Gordon M
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.