Understanding how brain cells communicate in the cerebral cortex
The origins of neuronal correlations in cerebral cortex
This study looks at how brain cells in the visual part of the brain work together when we see things, using special tools to observe these interactions in mice and monkeys, and it hopes to help us understand brain disorders that affect communication between these cells.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Chicago NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project ID | NIH-11057648 on NIH RePORTER |
What this research studies
This research investigates how pairs of neurons in the cerebral cortex interact and correlate with each other during various tasks, particularly focusing on visual processing. Using advanced techniques like two-photon microscopy and multielectrode arrays, the study will explore the mechanisms behind these correlations in both mice and macaques. By examining how these interactions change during visual stimuli and how different types of neurons contribute to these processes, the research aims to provide insights into the fundamental workings of the brain. Patients may benefit from a better understanding of brain disorders related to neuronal communication.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research would include individuals with neurological conditions affecting visual processing or cognitive functions.
Not a fit: Patients with conditions unrelated to neuronal communication or those not experiencing cognitive or visual impairments may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for brain disorders by enhancing our understanding of neuronal communication.
How similar studies have performed: Previous research has shown promising results in understanding neuronal correlations, making this approach a continuation of established findings in the field.
Where this research is happening
Chicago, United States
- University of Chicago — Chicago, United States (Active)
Researchers
- Principal investigator: Maclean, Jason Neil — University of Chicago
- Study coordinator: Maclean, Jason Neil
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.