NIH-funded research NIH-funded research

Understanding how brain activity changes after early life challenges

Official title: Mapping and Modulating Brain States

Funded at University of New Mexico Health Scis Ctr · NIH-11001818 · Data updated 2026-11-12

This study looks at how tough experiences in childhood can change the way our brains work when we face stress later in life, and it aims to help us find better ways to understand and treat mental and physical health issues that might come from those early challenges.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of New Mexico Health Scis Ctr
NIH-funded
Lab location1 site (Albuquerque, United States)
Project startJuly 1, 2024
Project endJune 30, 2026
Funding year2024
Award (this year)$39,403
NIH project number1F99NS139535-01
Project IDNIH-11001818 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are adults over 21 who have experienced early life adversity and are facing mental or physical health challenges.

Less likely to help

Patients who have not experienced early life adversity or do not have related mental or physical health issues may not benefit from this research.

What this research studies

This research investigates how different patterns of brain activity, known as brain states, are affected by early life adversity and subsequent exposure to threats. By using advanced imaging techniques and computational algorithms, the study aims to map these brain states and understand their role in mental and physical health. The research will involve longitudinal measurements to capture changes in brain activity over time, providing insights into how these changes can inform precision medicine approaches for better clinical outcomes. Patients may benefit from improved understanding and treatment options for conditions linked to early life experiences.

Why it matters

Potential benefit: If successful, this research could lead to more effective treatments for mental and physical disorders linked to early life adversity.

How similar studies have gone: Previous research has shown promise in using brain mapping techniques to understand neural activity patterns, suggesting that this approach could yield valuable insights.

Where this research is happening

  • University of New Mexico Health Scis Ctr
    Albuquerque, United States
    Active

Researchers

  • Principal investigator: Uselman, Taylor W — University of New Mexico Health Scis Ctr
  • Study coordinator: Uselman, Taylor W

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About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.