NIH-funded research NIH-funded research

GenomeCharacterization for AI/AN Cancer Health

Official title: Genome Characterization Unit

Funded at University of New Mexico Health Scis Ctr · NIH-11640964 · Data updated 2026-11-12

A large NIH project aims to map the cancer genomes of American Indian and Alaska Native people to uncover unique mutations and patterns that could improve cancer screening, prevention, and treatment for AI/AN communities.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of New Mexico Health Scis Ctr
NIH-funded
Lab location1 site (Albuquerque, United States)
Project startSeptember 2, 2020
Project endAugust 31, 2027
Funding year2026
Award (this year)$1,249,629
NIH project number5U2CCA252973-06
Project IDNIH-11640964 on NIH RePORTER

Who could benefit from this research

Could help

AI/AN individuals with cancer or at risk who participate in the study and community engagement activities.

Less likely to help

People who are not AI/AN or who do not participate in genomic sequencing or community engagement components may not directly benefit.

What this research studies

This program focuses on AI/AN populations who experience worse cancer outcomes. It plans to engage AI/AN participants and communities with respect and collaboration, and to perform comprehensive genomic sequencing of cancer samples. The goal is to identify germline and somatic mutations and mutational signatures that reflect distinct exposures, then translate findings into practical improvements in screening and prevention. The project is hosted at the University of New Mexico Health Sciences Center, led by Dr. Jeffrey M. Trent, and spans several years. It emphasizes culturally appropriate partnerships and data sharing to benefit AI/AN communities.

Why it matters

Potential benefit: If successful, the project could lead to earlier cancer detection and more personalized prevention and treatment strategies for AI/AN people.

How similar studies have gone: Previous cancer genomics efforts largely underrepresented AI/AN populations; this project seeks to address that gap with direct engagement and sequencing.

Where this research is happening

  • University of New Mexico Health Scis Ctr
    Albuquerque, United States
    Active

Researchers

  • Principal investigator: Trent, Jeffrey M. — University of New Mexico Health Scis Ctr
  • Study coordinator: Trent, Jeffrey M.

Related research

Other NIH-funded projects on the same topics.

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  • Administrative Core for a Cancer Research Program

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    NIH research University of New Mexico Health Scis Ctr · Albuquerque, United States · NIH-11644055

  • Administrative Core for a cancer research program

    A central hub at a major medical center helps coordinate cancer research, data resources, and compliance to accelerate progress for people affected by cancer.

    NIH research University of New Mexico Health Scis Ctr · Albuquerque, United States · NIH-11644052

  • Engagement Optimization for AI/AN Cancer Genomics and Care

    A patient-friendly project aims to use AI tools to better understand cancer genetics in American Indian and Alaska Native communities and use that knowledge to improve screening, prevention, and treatment.

    NIH research University of New Mexico Health Scis Ctr · Albuquerque, United States · NIH-11640965

  • Engaging AI/AN Communities in Cancer Genomics for Better Screening and Care

    A community-engaged research effort to understand cancer genetics in American Indian and Alaska Native people with the goal of improving screening, prevention, and treatment.

    NIH research University of New Mexico Health Scis Ctr · Albuquerque, United States · NIH-11640963

  • Engagement of AI/AN Communities in Cancer Genome Sequencing (Administrative Core)

    A dedicated program partners with American Indian and Alaska Native communities to explore cancer genomes and how sequencing information can improve screening, prevention, and treatment for AI/AN people.

    NIH research University of New Mexico Health Scis Ctr · Albuquerque, United States · NIH-11640962

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.